Date of Defense

Spring 4-1979

Department

Biological Sciences

First Advisor

Leonard Ginsberg, Biomedical Sciences

Abstract

Glycoprotein levels and types were determined by disc gel electrophoresis and PAS staining of the plasma of diabetic vs. non-diabetic chinese hamsters. The author found that the patterns of the bands in the disc gels varied among the lines. However, the total amount of glycoprotein was found to be generally the same in the diabetic lines as in the non-diabetic line, except for one diabetic line which had elevated glycoprotein levels, while another diabetic line had lower levels of glycoprotein than the normal. The results of this study indicate that there are differences among diabetic and non-diabetic lines in types of glycoproteins present, but that diabetes in the chinese hamster does not necessarily lead to increased levels of total glycoproteins in their plasma.

Access Setting

Honors Thesis-Campus Only

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