Date of Defense

11-30-2001

Department

Chemistry

First Advisor

Elke Schoffers, Chemistry

Second Advisor

Marc Perkovic, Chemistry

Third Advisor

Subra Murali, Chemistry

Abstract

The initial objective of our research was to develop a preparative method for optically active tropinone derivatives as key intermediates for organic synthesis. As the project got undsr way, difficulties with the literature procedure were encountered and a new project objective was delineated; it entailed the synthesis of 2,4,8-trimethyl-8-azabicyclo[3.2.1]oct-6-en-3-one (7), Scheme 3. The following sections will discuss our efforts toward the synthesis of intermediate 7 using a variation of Hoffmann's procedure.4 A special laboratory technique was developed to improve the preparation of this valuable synthetic precursor.

Access Setting

Honors Thesis-Campus Only

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