Date of Defense
Robert Eversole, Biological Sciences
John Jellies, Biological Sciences
Bone is a dynamic matter that provides support, structure, mineral reserves, and stem cell reserves for the body. Important functions range from structural support for the body to roles in maintaining homeostasis. Structure and support for the body is the most obvious role, with the skeletal system as a whole providing a normal force for other tissues and organs to resist gravity. Protection is also inferred for tissues and organs from impacting forces, especially with axial bones covering vital organs in the thoracic cavity. Another function of bone includes the ability to store and release minerals when needed to maintain appropriate levels in circulation. Specifically the resident mineral of bone tissue, hydroxyapatite, is composed mostly of calcium and phosphorus. Calcium and phosphorus are vital in essentially every system in the body, and so on. Bone has the ability to dissociated hydroxyapatite to release and provide these two elements to the body. Lastly, bone provides a location for the storage of stem cells, residing in bone marrow. These cells are vital to supplying new cells for the repair of tissue damage, resupplying the immunological system, generating erythrocytes for the circulatory system, and other functions requiring new cells.
Jones, Ryan T., "A Review of Literature for Osteology: Cell Biology, Tissue Biology, and the Application of Synthetic Compounds for the Facilitation of Bone Tissue Repair" (2011). Honors Theses. 81.
Honors Thesis-Open Access