Date of Award

6-1991

Degree Name

Master of Arts

Department

Psychology

First Advisor

Dr. Jack Michael

Second Advisor

Dr. Alan Poling

Third Advisor

Dr. Elbert Blakely

Access Setting

Masters Thesis-Open Access

Abstract

Acute and chronic effects of mephenytoin (30 - 360 mg/kg) were examined in pigeons responding under a multiple fixed-ratio 50 fixed-interval 90-sec schedule of food delivery. The highest dose administered acutely (240 mg/kg) produced substantial reductions in rate of responding under both components of the multiple schedule; the effects of other doses were small and inconsistent. Tolerance appeared to develop to the rate-decreasing effects of mephenytoin following chronic exposure to the drag.

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