Date of Award

4-1987

Degree Name

Master of Arts

Department

Psychology

First Advisor

Dr. Alan Poling

Second Advisor

Dr. Wayne Fuqua

Third Advisor

Dr. Jack Michael

Access Setting

Masters Thesis-Open Access

Abstract

Learning impairment is a potentially serious side effect of antiepilepsy medications. The present study investigated the effects of methsuximide and mephenytoin on learning in pigeons performing under a repeated acquisition procedure. Given acutely, methusuximide (25, 50, 75, 100 mg/kg) and mephenytoin (60, 120, 240 mg/kg) produced generally dose-dependent decreases in rates of responding; increases in percent errors were largest at doses that produced the greatest decrease in response rate. An analysis of the within-session distribution of errors revealed that certain

Included in

Psychology Commons

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