Date of Award

8-1984

Degree Name

Master of Arts

Department

Biological Sciences

First Advisor

Dr. Imy Holt

Second Advisor

Dr. David Cowan

Third Advisor

Dr. Leo VanderBeek

Access Setting

Masters Thesis-Open Access

Abstract

Two new benzodiazepine tranquilizers, alprazolam and triazolam were used to try to reduce aggression in rats produced by isolation or drugs. Both reduced elements of isolation-induced aggression, and triazolam was more potent. Little reduction was found in drug-induced aggression by either tranquilizer. It is unknown why aggression was not reduced for the drug-induced method, but it is possible that a synergism existed between the two methods of inducing aggression, since the same rats were used for both methods. Different rats were used for each tranquilizer. Reduction in aggression for the isolated rats seems consistent with results for other benzodiazepine tranquilizers.

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