Experimentation to Develop Procedures to be Used in the Investigation of the Effects of Restriction on the Unmodified DNA of the Bacteriophage Lamda

Author

John Haynes, Western Michigan UniversityFollow

Date of Defense

Summer 6-5-1973

Department

Biological Sciences

Keywords

λ

Abstract

The results of experimentation approximately twenty years ago with variuos bacteriophages by Ralston and Krueger¹⁶, Anderson and Felix¹, Luria and Human¹², and by Bertani and Weigle² have shown that the host range of a given phage depends directly on the bacterial strain on which the phage has last propagated. This event came to be known as host-induced modification or host-controlled variation. As this phage host range is controlled by the host environment and can be altered from one generation to another it has, according to Luria, made microbiology "the last stronghold of Lamarckism"¹¹. This paper explores the groundwork research laid on the study of bacteriophages, and also provides procedures used to investigate the bacteriophate Lambda.

Recommended Citation

Haynes, John, "Experimentation to Develop Procedures to be Used in the Investigation of the Effects of Restriction on the Unmodified DNA of the Bacteriophage Lamda" (1973). Honors Theses. 187.
https://scholarworks.wmich.edu/honors_theses/187

Access Setting

Honors Thesis-Open Access