Date of Defense

12-1-2014

Date of Graduation

12-2014

Department

Biological Sciences

First Advisor

Elke Schoffers

Second Advisor

Steve Bertman

Third Advisor

Silvia Rossbach

Abstract

Hexahydrolupulone, derived from hop beta acids, has great potential as an antimicrobial agent. This study focused on the synthesis and characterization of ester derivatives of hexahydrolupulone and their antimicrobial effects on four microorganisms including Staphylococcus aureus, Enterococcus faecalis, Pseudomona aeruginosa, and Escherichia coli. Analysis of the ester derivatives was done through IR and proton NMR spectroscopy. Testing of the antimicrobial effects of each compound was accomplished using the disk assay method.

Access Setting

Honors Thesis-Restricted

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