Date of Defense
Oxazolidinones are a relatively new class of antibacterial agents on the threshold of discovery. Their potential activity has been demonstrated in vitro and in animal models of infection with common pathogens including multi-drug resistant strains. Although of the six analogs produced here, none were more active than vancomyacin against these pathogens, there is still much to be learned about the mode of action of oxazolidinone compounds.
Adamski, Jennifer L., "Oxazolidinones: Halopyridine Analogs in Synthetic Antibiotic Development" (1998). Honors Theses. 631.
Honors Thesis-Campus Only