Date of Award
Master of Arts
Dr. Robert E. Harmon
Dr. Donald Berndt
Dr. Ralph Steinhaus
Masters Thesis-Open Access
This research project consists of two parts. The first involved the synthesis of a novel quininoxaline di-N-oxide via benzofuroxan. The second part was the use of this compound as a synthetic precursor.
It was assumed that 3,4-dimethylaniline would be successfully converted to 5,6-dimethybenzofurazan 1-oxide (5,6-dimethybenzofuroxan) through a sequence of reaction steps. Fortunately, this assumption was correct as the desired compound was produced. This compound was utilized in synthesizing the novel 3-acetyl-2,6,7-trimethylquinoxaline 1,4-dioxide. From the structure of this adduct, it is believed that it will take part in condensation reactions associated with methyl ketones without disrupting the quinoxaline di-N-oxide framework, and this is demonstrated by its reactions with a variety of aromatic aldehydes.
Some portions of 3-acetyl-2,6,7-trimethylquinoxaline 1,4-dioxide were reacted with aromatic aldehydes to produce 3-acyl-2,6,7-trimethylquinoxaline 1,4-dioxides which are novel. The reaction descriptions, spectra, and microanalyses will help to clarify these findings.
Ogbu, Cyprian Okwara, "Synthesis and Study of Novel Quinoxaline Di-N-oxide and 3-Acyl-2-Methylquinoxaline Di-N-oxides" (1988). Masters Theses. 1135.