Author

Bauer

Date of Award

1-1962

Degree Name

Master of Arts

Department

Chemistry

First Advisor

Dr. Robert Nagler

Second Advisor

Lillian H. Meyer

Third Advisor

Don C. Iffland

Access Setting

Masters Thesis-Open Access

Abstract

Introduction

Compounds of the amidine class have long been of interest because of their therapeutic and pharmacological properties. Members of this class of compounds have been shown to be effective in combating pathological conditions ranging from virus (11), bacterial (12), and protozoal infections (7) to diseases of the circulatory system (6), neoplasms (5) and hyperglucemia (21), Since many basic nitrogen compounds have been of interest in cancer chemotherapy, such as a variety of amino alcohols shown by the Upjohn Company to have anti-tumoral activity, it was felt that additional investigations into the use of amidines and amino amidines in this area would be justified.

Included in

Chemistry Commons

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