Date of Defense
Frequently, oncologists prescribe antidepressant drugs to cancer patients suffering from depression as a side-effect of cancer chemotheraphy. Little research has investigated the possible deleterious behavioral effects of these drugs when given in combination. The present experiment demonstrates behavioral depression resulting from the combined administration of pro carbazine, an antineoplastic agent, and imipramine, a tricyclic antidepressant. Running wheels were used as a measure of activity in mice.
King, Katherine A.J., "Locomotion: Effects of Procarbazine and Imipramine on Male and Female CD-1 Mice" (1983). Honors Theses. 1178.
Honors Thesis-Campus Only