A Synthetic Approach to Novel Heterocyclic Herbicides

Author

Paul Antony Pathadan, Western Michigan University

Date of Award

4-1988

Degree Name

Master of Arts

Department

Chemistry

First Advisor

Dr. Robert E. Harmon

Second Advisor

Dr. Lindsley J. Foote

Third Advisor

Dr. Donald C. Berndt

Access Setting

Masters Thesis-Open Access

Abstract

The purpose of this research study was to prepare novel heterocyclic herbicides. The first phase of the project was to synthesize 1-(nitromethyl)-4-phthalazone.

In the second phase 1 - (nitromethyl)-4-phthalazone was treated with 1,3-propane-dithio-di-p-toluene sulfonate in presence of sodium hydride to get the target compound 4-(1'-nitro-l,3-dithiane)phthalazone.

It is believed that this compound might block the electron transport system of aerobic cells¹ . So further investigation of this compound may lead to novel herbicides.

Recommended Citation

Pathadan, Paul Antony, "A Synthetic Approach to Novel Heterocyclic Herbicides" (1988). Masters Theses. 1181.
https://scholarworks.wmich.edu/masters_theses/1181