Date of Award
Master of Science
Dr. Elke Schoffers
Dr. Marc W. Perkovic
Dr. James Kiddle
Masters Thesis-Open Access
Asymmetric catalysis can provide a general approach to the preparation of enantiomerically enriched compounds in organic synthesis. Very often these asymmetric catalysts consist of a chiral ligand-metal complex. Because of the growing demand to develop enantioselective reactions in organic chemistry one focus of this area of research is the design and characterization of new chiral ligands for asymmetric synthesis.
The focus of my research is in the design, synthesis, and characterization of novel 1, 10-phenanthroline derivatives that could be used as chiral ligands in enantioselective reactions. Central to these studies have been the effect of substituents on the B-ring of 1, 10-phenanthroline. The derivatives were prepared from epoxide via ring opening with various nucleophiles. These fully characterized new compounds were then examined for their ability to coordinate a diverse set of transition metals in order to explore their potential as asymmetric catalysts.
Kim, "Synthetic and Structural Studies of Novel 1, 10-Phenanthroline Derivatives" (2005). Master's Theses. 4330.