Side Chain Effect on Micellarly Catalyzed Hydrolysis of Hydroxamic Acids in Perfluorooctanoic Acid Environment
Date of Award
Master of Arts
Dr. Donald C. Berndt
Dr. Steve Bertman
Dr. Donald Schreiber
Masters Thesis-Open Access
The side chain effect on micellar catalysis of hydroxamic acids with perfluorooctanoic acid as the reactive counterion surfactant in aqueous acetonitrile solution has been demonstrated in this thesis.
The rate constant-surfactant concentration profiles were used to estimate the critical micelle concentration and the second order rate constant for hydrolysis in the aqueous bulk phase.
The pseudo-phase ion exchange model satisfactorily explains the surfactant effect. The second order rate constants in the aqueous bulk phase show a direct relationship with steric substituent constants. The major influence of the change in micellar catalysis is the location in the micelle where the substrate is bound.
Further investigation regarding the location in the micelle where hydroxamic acids are bound is suggested.
Fernando, A.C. Menik, "Side Chain Effect on Micellarly Catalyzed Hydrolysis of Hydroxamic Acids in Perfluorooctanoic Acid Environment" (1996). Masters Theses. 4355.