Cocaine and Timing: Drug Effects Under a Mixed Fixed-Interval Extinction Schedule

Author

Vincent O. Hodge

Date of Award

8-1991

Degree Name

Master of Arts

Department

Psychology

First Advisor

Dr. Alan D. Poling

Second Advisor

Dr. Frederick Gault

Third Advisor

Dr. Jack Michael

Fourth Advisor

Dr. Roger Ulrich

Access Setting

Masters Thesis-Open Access

Abstract

The effects of cocaine hydrochloride (3.2-56.2 mg/kg) were determined in rats performing under a mixed fixed-interval 60-seconds extinction 120-seconds schedule of food delivery. Responses were recorded in successive 5-second bins. With the exception of the highest dose (56.2 mg/kg), cocaine did not significantly affect rate of responding under the fixed-interval component or extinction component, or the time of peak responding under the extinction component. The highest dose significantly reduced response rates and shifted the time of peak responding leftward to quicker and earlier moments. Results are discussed in terms of possible rate- and time-dependent effects of stimulant drugs.

Recommended Citation

Hodge, Vincent O., "Cocaine and Timing: Drug Effects Under a Mixed Fixed-Interval Extinction Schedule" (1991). Masters Theses. 999.
https://scholarworks.wmich.edu/masters_theses/999