Thromboelastography Following Liver Resection

Authors

Brandon Tanner M.D., Western Michigan University Homer Stryker M.D. School of MedicineFollow
Gitonga Munene M.D., Western Michigan University Homer Stryker M.D. School of MedicineFollow
Steven Lu M.D., Western Michigan University Homer Stryker M.D. School of MedicineFollow
Richa Khatri M.D., Western Michigan University Homer Stryker M.D. School of MedicineFollow

Document Type

Abstract

Date

2017

Abstract

BACKGROUND: This study was aimed at examining the predominant coagulation profile following liver resection. OBJECTIVE: Study the TEG profile following liver resection. METHODS: Patients undergoing liver resection were prospectively enrolled in the study. Perioperative variables were obtained and the TEG AND PT/INR were obtained preoperatively, post-operatively, and on POD# 1, 3, and 5. RESULTS: 17 patients were enrolled with a median age of 61, 35.3 % were female undergoing resection for either primary or metastatic disease. 35.3% underwent major hepatectomy, median EBL was 350mL, and the median LOS was 6 days, with a morbidity of 35.3% and no mortality. Post-operatively the TEG profile demonstrated a hypercoagulable profile in 92.8%, 64.2%, 57.1% and 42.8% of patients immediately post-operatively, and on POD# 1, 3, and 5 respectively. Despite multiple elevations in PT/INR in all the time points there was no concordance with the TEG profile. CONCLUSION: The TEG profile demonstrated a hypercoagulable profile in majority of patients undergoing liver resection despite an elevated PT/INR.