Date of Defense

4-6-1999

Department

Chemistry

First Advisor

John Chateauneuf, Chemistry

Second Advisor

Atli Thorarensen, Pharmacia & Upjohn

Abstract

The synthesis of unsymmetrical bispyrimidines via coupling of a halopyrimidine and pyrimidine thiolate anion was investigated utilizing palladium (0) catalyzed crosscoupling. Specific parameters such as solvent and stoichiometry were explored and optimized. The reaction conditions presented have allowed for the preparation of a wide variety of functional pyrimidines.

Access Setting

Honors Thesis-Campus Only

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