Date of Award

12-2017

Degree Name

Doctor of Philosophy

Department

Statistics

First Advisor

Dr. Joshua D. Naranjo

Second Advisor

Dr. Magdalena Niewiadomska-Bugaj

Third Advisor

Dr. Mathew Anthony C. Rosales

Keywords

Survival analysis, stratified Logrank diagnostic, stratified Wilcoxon diagnostic, adjusting for covariates, adaptive test

Abstract

Martinez and Naranjo (2010) proposed a pretest for choosing between Logrank or Wilcoxon test in a two - sample case. However, in the presence of covariates, comparing two populations without adjusting for covariates would yield misleading results. In this study, we propose several pretests that will help the analyst decide to use stratified Logrank or stratified Wilcoxon tests in comparing two survival curves after covariates have been taken into account. Power performance of each adaptive test was done through simulations under PH and non-PH cases.

Access Setting

Dissertation-Open Access

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