Synthetic Studies of 1,10-Phenanthroline Derivatives as Novel Catalysis Ligands and Their Application in Transition Metals Catalyzed Reactions

Author

Son Duc Tran, Western Michigan University

Date of Award

4-2006

Degree Name

Doctor of Philosophy

Department

Chemistry

First Advisor

Dr. Elke Schoffers

Second Advisor

Dr. James Kiddle

Third Advisor

Dr. Jay Means

Fourth Advisor

Dr. Marc Perkovic

Abstract

The preparation of 1,10-phenanthroline derivatives entailed ring opening reactions of 1,10-phenanthroline epoxide as a key transformation, affording novelbidentate nitrogen ligands with new stereogenic centers in the 5- and 6-position. This research was concerned with (i) the epoxidation of 1,10-phen, (ii) epoxide ring opening reactions, (iii) the formation of trans -5,6-disubstituted-1,10-phenanthroline metal complexes, and (iv) application of 1,10-phenanthroline derivatives in metal-catalyze reactions such as palladium-catalyzed allylic substitution and aminohalogenation reactions; Zinc-catalyzed direct aldolreaction, and acetophenone reduction; Nickel-catalyzed Michael addition reaction.

Comments

5th Advisor: Dr. Silvia Rossbach

Access Setting

Dissertation-Open Access

Recommended Citation

Tran, Son Duc, "Synthetic Studies of 1,10-Phenanthroline Derivatives as Novel Catalysis Ligands and Their Application in Transition Metals Catalyzed Reactions" (2006). Dissertations. 998.
https://scholarworks.wmich.edu/dissertations/998