Synthetic Studies of 1,10-Phenanthroline Derivatives as Novel Catalysis Ligands and Their Application in Transition Metals Catalyzed Reactions
Date of Award
Doctor of Philosophy
Dr. Elke Schoffers
Dr. James Kiddle
Dr. Jay Means
Dr. Marc Perkovic
The preparation of 1,10-phenanthroline derivatives entailed ring opening reactions of 1,10-phenanthroline epoxide as a key transformation, affording novelbidentate nitrogen ligands with new stereogenic centers in the 5- and 6-position. This research was concerned with (i) the epoxidation of 1,10-phen, (ii) epoxide ring opening reactions, (iii) the formation of trans -5,6-disubstituted-1,10-phenanthroline metal complexes, and (iv) application of 1,10-phenanthroline derivatives in metal-catalyze reactions such as palladium-catalyzed allylic substitution and aminohalogenation reactions; Zinc-catalyzed direct aldolreaction, and acetophenone reduction; Nickel-catalyzed Michael addition reaction.
Tran, Son Duc, "Synthetic Studies of 1,10-Phenanthroline Derivatives as Novel Catalysis Ligands and Their Application in Transition Metals Catalyzed Reactions" (2006). Dissertations. 998.
5th Advisor: Dr. Silvia Rossbach