Date of Defense
Diabetes mellitus, in essence, is an enigma. Researchers are still mystified about this disease which has been known about since ancient times. The modern investigator now recognizes that he is dealing with a complex, multifaceted disease, and not with a simple metabolic disturbance. The inability to perform experimental studies utilizing diabetic humans has created a need for an appropriate animal model. The Chinese Hamster (Cricetulus griseus) has been shown to offer a number of advantages as an animal for diabetes mellitus. A light microscopic examination of the ileum and anterior large intestine was undertaken to determine and quantify the morbid anatomy associated with the diabetic syndrome of the Chinese hamster in a state of ketosis.
Pozivilko, Mary, "Histopathology Associated with Ketoacidosis in the Ileum and Colon of the Chinese Hamster" (1975). Honors Theses. 242.
Honors Thesis-Campus Only