Date of Defense
Adrian Vanderwielen, The Upjohn Company
Kevin Jenkins, The Upjohn Company
Donald Schreiber, Chemistry
Upjohn, cleaning procedures, assay development, cleaning validation
Frequently, the same equipment will be used to produce different drugs. Thoroughly cleaning equipment between products is the best way to avoid potentially dangerous cross-contamination. Therefore, every product which Upjohn manufactures has a cleaning validation process. For standard solutions all methods work equally well.
Kowalski, Eileen M., "Cleaning Validation with total Organic Carbon Analysis" (1991). Honors Theses. 719.
Honors Thesis-Campus Only