Date of Award
4-1970
Degree Name
Master of Arts
Department
Psychology
First Advisor
Dr. Chris Koronakos
Second Advisor
Dr. Gyula Ficsor
Third Advisor
Dr. Howard Farris
Fourth Advisor
Dr. Donald Whaley
Access Setting
Masters Thesis-Open Access
Abstract
Earlier studies using both mice and rats have revealed a significant, positive correlation between preference of alcohol concentration and activity of the liver enzyme, alcohol dehydrogenase. In this study two groups of Sprague- Dawley rats, matched for sex, were presented alcohol by either a choice or forced condition for three twelve day periods in a choice-forced-choice or forced-choice-forced sequence. Data were recorded as the amount of alcohol - consumed under each consumption condition. After the rats were sacrificed, their livers were removed and assays were made for the alcohol dehydrogenase activity. While several correlations between consumption and alcohol dehydrogenase activity were significant, it was concluded that the results did not support the hypothesis that consumption of high concentrations of alcohol is a function of the organism metabolic capacity for alcohol exclusively.
Recommended Citation
Gray, David Bertsch, "A Comparison of Choice and Forced Alcohol Consumption and Alcohol Dehydrogenase Activity" (1970). Masters Theses. 2986.
https://scholarworks.wmich.edu/masters_theses/2986