Author

Weerasinghe

Date of Award

12-2007

Degree Name

Master of Science

Department

Chemistry

First Advisor

Dr. Ekkehard Sinn

Second Advisor

Dr. Subra Muralidharan

Third Advisor

Dr. James Kiddle

Fourth Advisor

Dr. Yirong Mo

Access Setting

Masters Thesis-Open Access

Abstract

Five novel 2,2 '-bis bi pyridine Ru(II) complexes have been synthesized and characterized using 1H NMR, 13C NMR, 1H-1H-COSY, elemental analysis, fast atom bombardment or electrospray mass spectra and electronic absorption spectroscopy. Binding of Ru (11) complexes with nerve gas analogos such as diethyl chlorophosphate (DCP), dimethyl methyl phosphonate (DMMP) and hydrolyzed product (HCl) has been investigated by electronic absorption, fluorescence, and lifetime studies. Compound 1 showed a quenching in 3MLCT emission after an initial increase in intensity upon the addition of DCP with a bathochromic shift of 25 nm. Compound 2 exhibit a small bathochromic shift of 5 nm with a continuous increase in emission with the continuous addition ofDCP. Lifetime studies of both compound 1 and 2 established the formation of a short lived adduct with DCP. Binding studies of compound 4 with DCP showed the amide nitrogen is not involved in binding with DCP. Compound 3 was found to be unstable and not effective against DCP or HCI. Compound 5 showed an increase in the emission with a red shift and was found to be effective against DCP and HCI. In addition, there was a distinct color change from green to red with both DCP and HCI. All five complexes did not show a reasonable response with DMMP suggesting the importance of a good leaving group attached to the phosphorus atom.

Included in

Chemistry Commons

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