Date of Award
1-1962
Degree Name
Master of Arts
Department
Chemistry
First Advisor
Dr. Robert Nagler
Second Advisor
Lillian H. Meyer
Third Advisor
Don C. Iffland
Access Setting
Masters Thesis-Open Access
Abstract
Introduction
Compounds of the amidine class have long been of interest because of their therapeutic and pharmacological properties. Members of this class of compounds have been shown to be effective in combating pathological conditions ranging from virus (11), bacterial (12), and protozoal infections (7) to diseases of the circulatory system (6), neoplasms (5) and hyperglucemia (21), Since many basic nitrogen compounds have been of interest in cancer chemotherapy, such as a variety of amino alcohols shown by the Upjohn Company to have anti-tumoral activity, it was felt that additional investigations into the use of amidines and amino amidines in this area would be justified.
Recommended Citation
Bauer, Robert, "The Reaction of N-Magnesium Halides on Nitriles in the Synthesis of Amidines" (1962). Masters Theses. 4398.
https://scholarworks.wmich.edu/masters_theses/4398